Description

(1R)-7β-Ethyl-1,2,3,4,4A,5,6,7,8,9,10,10Aα-Dodecahydro-1,4Aβ,7-Trimethyl-1α-Phenanthrenecarboxylic Acid Methyl Ester is a high-purity, stereochemically defined synthetic intermediate of significant importance in advanced organic synthesis. This compound is valued for its complex, rigid polycyclic structure, which serves as a critical building block in the development of novel pharmaceutical actives and fine chemicals. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, process development, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in steroid-like or terpenoid-based drug discovery programs.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for constructing complex molecular libraries to explore structure-activity relationships (SAR).
• Process Chemistry & Scale-up: Serves as a critical intermediate in the optimization and pilot-scale synthesis of target active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, fragrances, and advanced materials requiring a defined stereochemical core.
• Academic Research: Utilized in university and institutional labs for methodological studies in asymmetric synthesis, catalysis, and total synthesis projects.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(1R)-7β-Ethyl-1,2,3,4,4A,5,6,7,8,9,10,10Aα-Dodecahydro-1,4Aβ,7-Trimethyl-1α-Phenanthrenecarboxylic Acid Methyl Ester
CAS No.	3582-25-0
Molecular Formula	C21H34O2
Molecular Weight	318.50 g/mol
Synonyms	Methyl (1R,4aS,7S,10aR)-7-Ethyl-1,4a,7-trimethyl-1,2,3,4,4a,5,6,7,8,9,10,10a-dodecahydrophenanthrene-1-carboxylate; (1R,4aS,7S,10aR)-7-Ethyl-1,4a,7-trimethyl-1,2,3,4,4a,5,6,7,8,9,10,10a-dodecahydrophenanthrene-1-carboxylic Acid Methyl Ester; 7β-Ethyl-1,2,3,4,4a,5,6,7,8,9,10,10aα-dodecahydro-1,4aβ,7-trimethyl-1α-phenanthrenecarboxylic Acid Methyl Ester; Methyl 7β-Ethyl-1,2,3,4,4a,5,6,7,8,9,10,10aα-dodecahydro-1,4aβ,7-trimethyl-1α-phenanthrenecarboxylate; Steroid Synthesis Intermediate; Chiral Phenanthrene Ester.
EINECS	Contact for details

Quality Control

Our production of (1R)-7β-Ethyl-1,2,3,4,4A,5,6,7,8,9,10,10Aα-Dodecahydro-1,4Aβ,7-Trimethyl-1α-Phenanthrenecarboxylic Acid Methyl Ester adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including chiral HPLC, NMR, and GC/MS, to confirm identity, stereochemical purity, and chemical purity. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.