Description

Amidinomycin is a biologically active amidine-containing natural product with antibiotic and antifungal properties, originally isolated from Streptomyces species. It serves as a valuable reference standard and research tool in antimicrobial mechanism studies, drug discovery, and structure–activity relationship (SAR) profiling. Researchers in pharmaceutical development, academic microbiology labs, and contract research organizations (CROs) rely on high-purity Amidinomycin CAS NO 3572-60-9 for target validation and assay calibration.

Application

• Antibiotic mode-of-action studies targeting bacterial cell wall synthesis and protein translation
• Reference standard for HPLC and LC-MS method development and validation in antimicrobial analysis
• Lead compound in medicinal chemistry programs exploring amidine-based inhibitors
• In vitro antifungal screening against Candida and Aspergillus strains
• Quality control benchmark for biosynthetic analogues and semi-synthetic derivatives
• Tool compound in resistance mechanism research (e.g., efflux pump or ribosomal protection studies)
• Calibration material for quantitative bioassays measuring minimum inhibitory concentration (MIC)
• Stability-indicating reference in forced degradation studies of nitrogen-rich antibiotics

Basic Information

Product Name	Amidinomycin
CAS No.	3572-60-9
Molecular Formula	C15H20N4O3
Molecular Weight	304.35 g/mol
Synonyms	Amidinomycin; NSC 121591; Antibiotic AM-1; Streptomyces-derived amidine antibiotic; 2-(Aminomethylideneamino)-N-(2-hydroxyethyl)-5-methyl-1H-pyrrole-3-carboxamide; 3-[(2-Hydroxyethyl)carbamoyl]-2-[(aminomethylene)amino]-5-methyl-1H-pyrrole; AM-1; Amidino-mycin
EINECS	222-667-8

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. Each batch is verified for identity (IR, HPLC retention time), purity (≥98.5% by HPLC), and absence of specified impurities (heavy metals, residual solvents, microbial contamination). Testing follows ACS Reagent Grade and EP/USP general chapters where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at 2–8 °C under inert atmosphere (nitrogen or argon) to prevent oxidation and moisture uptake. Due to its hygroscopic nature, minimize exposure to ambient humidity during handling. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.5% – 101.0%
Related Substances (HPLC)	≤1.5% total impurities
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.