Description

Benzhydryl Isothiocyanate is a versatile organic building block characterized by its reactive isothiocyanate (-N=C=S) functional group attached to a benzhydryl core. This compound matters for its role as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. Industries that need it include agrochemical developers, pharmaceutical companies, and academic research institutions focused on creating novel thiourea derivatives, enzyme inhibitors, or bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those targeting enzymes or receptors where the thiourea moiety is pharmacologically active.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the isothiocyanate group can be used to introduce sulfur-containing functional groups.
• Chemical Biology Research: Serves as a reagent for bioconjugation and labeling of biomolecules (proteins, peptides) due to the reactivity of the isothiocyanate group with amines.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials that require the benzhydryl scaffold.
• Polymer Chemistry: Can act as a monomer or cross-linking agent in the production of specialty polymers with unique thermal or mechanical properties.
• Ligand Synthesis for Catalysis: Used to prepare thiourea-based ligands for metal complexes in asymmetric catalysis and organic transformations.

Basic Information

Item	Details
Product Name	Benzhydryl Isothiocyanate
CAS No.	3550-21-8
Molecular Formula	C15H13NS
Molecular Weight	239.34 g/mol
Synonyms	Diphenylmethyl isothiocyanate; (Diphenylmethyl)isothiocyanate; α-Isothiocyanatodiphenylmethane; NSC 403697; Benzhydryl mustard oil; Diphenylmethane, α-isothiocyanato-; Benzhydrylisothiocyanat
EINECS	Contact for details

Quality Control

Our Benzhydryl Isothiocyanate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents and amines. Due to its reactivity, it should be handled and stored under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.