Description

1-[(2R,4S,5S)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-5-Methyl-Pyrimid Ine-2,4-Dione is a high-purity nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of modified nucleosides and nucleotides, which are essential in antiviral and anticancer therapeutic agents. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and diagnostic probes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or standard in enzymatic studies and metabolic pathway analysis.
• Nucleic Acid Chemistry: Serves as a modified building block for oligonucleotide synthesis, enabling the study of structure-activity relationships.
• Diagnostic Development: Employed in the creation of labeled probes and tools for molecular diagnostics and genomic research.
• Process Development: Utilized in scaling up and optimizing synthetic routes for complex nucleoside-based Active Pharmaceutical Ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical manufacturing.

Basic Information

Product Name	1-[(2R,4S,5S)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-5-Methyl-Pyrimid Ine-2,4-Dione
CAS No.	3545-96-8
Molecular Formula	C10H14N2O6
Molecular Weight	258.23 g/mol
Synonyms	5-Methyluridine; Ribothymidine; 1-[(2R,4S,5S)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione; 5-Methyl-Uridine; Thymine Riboside; 2'-Deoxythymidine (Note: This is a common mis-association; verify structure); T (as a nucleoside symbol); Contact for additional synonyms.
EINECS	222-594-8

Quality Control

Our 1-[(2R,4S,5S)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-5-Methyl-Pyrimid Ine-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.