Description

3,4-Dimethoxybenzoyl Chloride CAS NO 3535-37-3 is a versatile and highly reactive aromatic acid chloride derivative. It serves as a critical building block in organic synthesis, enabling the efficient introduction of the 3,4-dimethoxybenzoyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), advanced intermediates, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), especially those targeting the central nervous system.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the dimethoxybenzoyl group imparts specific biological activity.
• Fine Chemical Building Block: Employed in the manufacture of dyes, pigments, and photoinitiators for polymer chemistry.
• Peptide Coupling Reagent: Acts as a coupling agent or protecting group reagent in peptide synthesis and other amide bond formation reactions.
• Liquid Crystal & Polymer Research: Serves as a monomer or intermediate in the development of specialty polymers and liquid crystal materials.
• Laboratory & R&D: Utilized in academic and industrial research for method development and exploring new synthetic pathways.

Basic Information

Product Name	3,4-Dimethoxybenzoyl Chloride
CAS No.	3535-37-3
Molecular Formula	C9H9ClO3
Molecular Weight	200.62 g/mol
Synonyms	Veratroyl Chloride; 3,4-Dimethoxybenzoyl chloride; 3,4-Dimethoxybenzoic acid chloride; 3,4-Dimethoxy-benzoylchlorid; NSC 403119; Benzoic acid, 3,4-dimethoxy-, chloride; 3,4-Dimethoxybenzoylchloride
EINECS	222-562-6

Quality Control

Our 3,4-Dimethoxybenzoyl Chloride is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP starting materials and ensures reliability for critical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and maintain stability. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.