Description

3-Nitrophenyl Isothiocyanate is a versatile aromatic isothiocyanate derivative characterized by its reactive isothiocyanate (-N=C=S) group and electron-withdrawing nitro substituent. This compound is a critical building block in organic synthesis, enabling the efficient introduction of the thiourea moiety into target molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thiourea-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe: Serves as a reactive handle for labeling and modifying proteins, peptides, and other biomolecules to study biological processes.
• Material Science: Building block for creating functional polymers, liquid crystals, and advanced organic materials with specific electronic or optical properties.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and colorants due to its aromatic nitro-isothiocyanate structure.
• Cross-linking Agent: Can be used to create covalent linkages between molecules in polymer chemistry and surface modification.

Basic Information

Product Name	3-Nitrophenyl Isothiocyanate
CAS No.	3529-82-6
Molecular Formula	C7H4N2O2S
Molecular Weight	180.18 g/mol
Synonyms	m-Nitrophenyl Isothiocyanate; 3-Nitrobenzenecarbothioic Acid Isothiocyanate; 1-Isothiocyanato-3-nitrobenzene; 3-Nitrobenzenecarbothioic Acid, Isothiocyanate; 3-Nitrobenzenecarbothioic Acid, Isothiocyanate Ester; 3-Nitro Phenyl Isothiocyanate; m-Nitro Phenyl Isothiocyanate; 3-Nitrobenzenecarbothioic Acid Isothiocyanate Ester
EINECS	222-552-9

Quality Control

Our 3-Nitrophenyl Isothiocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.