Description

(25R)-3β-Hydroxy-5α-Spirost-9(11)-En-12-One is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of complex pharmaceutical compounds. Its defined stereochemistry and specific functional groups make it a valuable building block for research and development in medicinal chemistry. This compound is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise, high-quality intermediates for steroid-based drug discovery and production.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of steroidal drugs, including potential anti-inflammatory, hormonal, and cardiovascular agents.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and the development of novel therapeutic compounds targeting specific biological pathways.
• Fine Chemical Synthesis: Used in the production of specialized, high-value chemical products where the specific (25R) configuration and spirostan skeleton are required.
• Reference Standard: Employed as an analytical standard in quality control laboratories for the identification and quantification of related steroid compounds.
• Biochemical Research: Utilized in studies investigating steroid biosynthesis, metabolism, and receptor interactions due to its specific structural features.

Basic Information

Product Name	(25R)-3β-Hydroxy-5α-Spirost-9(11)-En-12-One
CAS No.	3514-26-9
Molecular Formula	C27H38O4
Molecular Weight	426.59 g/mol
Synonyms	12-Oxotigogenin; 3β-Hydroxy-5α-spirost-9(11)-en-12-one; (25R)-Spirost-9(11)-en-12-one, 3β-hydroxy-5α-; Tigogenone; 9(11)-Dehydrotigogenin-12-one; Tigogen-12-one; 5α-Spirost-9(11)-en-12-one, 3β-hydroxy-, (25R)-
EINECS	Contact for details

Quality Control

Our (25R)-3β-Hydroxy-5α-Spirost-9(11)-En-12-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.