Description

5'-Deoxythymidine is a fundamental nucleoside derivative, serving as a critical building block in nucleic acid chemistry and biochemistry. Its primary value lies in its role as a precursor for the synthesis of modified nucleotides, oligonucleotides, and various antiviral or anticancer prodrugs. This high-purity intermediate is essential for research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in nucleoside-based drug discovery, diagnostic assay development, and biochemical research.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used as a monomeric building block in solid-phase and solution-phase synthesis of DNA strands and probes.
• Biochemical Research: Essential substrate for enzymatic studies involving thymidine kinase and other nucleoside-metabolizing enzymes.
• Diagnostic Reagents: Component in the manufacture of labeled nucleotides for use in sequencing, PCR, and microarray technologies.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical and life science industries.

Basic Information

Product Name	5'-Deoxythymidine
CAS No.	3458-14-8
Molecular Formula	C10H14N2O5
Molecular Weight	242.23 g/mol
Synonyms	Thymidine; 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil; 2'-Deoxythymidine; dT; D-Thymidine; 5-Methyl-2'-deoxyuridine; NSC 21548
EINECS	222-399-0

Quality Control

Our 5'-Deoxythymidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material that meets in-house specifications and can discuss compliance with relevant pharmacopeial standards (e.g., USP, EP) for specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.