Description

3-(Phenylsulfonyl)Propanoyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, primarily used as a key building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 3-(phenylsulfonyl)propanoyl moiety, a functional group of significant interest in medicinal chemistry and material science. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting enzyme inhibition or requiring specific sulfone-based pharmacophores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the phenylsulfonyl group contributes to biological activity.
• Polymer & Material Science: Serves as a monomer or modifying agent for creating specialty polymers with tailored properties like thermal stability or specific reactivity.
• Organic Synthesis Reagent: Employed in peptide coupling reactions and as an acylating agent for amines and alcohols in complex molecule construction.
• Ligand & Catalyst Development: Useful for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Chemical Research: A valuable tool for academic and industrial R&D departments exploring new synthetic methodologies and compound libraries.

Basic Information

Item	Detail
Product Name	3-(Phenylsulfonyl)Propanoyl Chloride
CAS No.	3445-53-2
Molecular Formula	C9H9ClO3S
Molecular Weight	232.68 g/mol
Synonyms	3-(Benzenesulfonyl)propanoyl chloride; 3-(Phenylsulfonyl)propionyl chloride; β-(Phenylsulfonyl)propionyl chloride; 3-Oxo-3-(phenylsulfonyl)propyl chloride; Propanoyl chloride, 3-(phenylsulfonyl)-; NSC 163082
EINECS	222-357-7

Quality Control

Our 3-(Phenylsulfonyl)Propanoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.