Description

5'-Deoxy-8,5'-Cycloadenosine is a chemically modified nucleoside analog characterized by its unique cyclized structure. This compound is of significant interest in advanced pharmaceutical research and development, particularly in the study of nucleic acid chemistry and as a potential building block for novel therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in the synthesis of nucleotide-based drugs, antiviral agents, and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and DNA/RNA repair mechanisms.
• Pro-drug Development: Acts as a building block for creating targeted nucleotide pro-drugs designed for improved cellular uptake and metabolic stability.
• Antiviral Agent Research: Investigated for its potential activity against viral polymerases due to its structurally modified ribose moiety.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis: Utilized as a sophisticated chiral synthon in complex organic synthesis for introducing the adenosine scaffold.

Basic Information

Product Name	5'-Deoxy-8,5'-Cycloadenosine
CAS No.	3415-89-2
Molecular Formula	C11H13N5O3
Molecular Weight	263.26 g/mol
Synonyms	8,5'-Cyclo-5'-deoxyadenosine; 8,5'-Cycloadenosine, 5'-deoxy-; 5'-Deoxy-8,5'-cycloadenosine; Adenosine, 5'-deoxy-8,5'-cyclo-; 1-(5-Deoxy-β-D-erythro-pent-4-enofuranosyl)-1H-imidazo[4,5-d][1,3]diazepin-4-amine; 8,5'-anhydro-5'-deoxyadenosine
EINECS	Contact for details

Quality Control

Our 5'-Deoxy-8,5'-Cycloadenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.