Description

5-(2,4-Dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolane-2-carboxylic acid is a high-purity nucleoside derivative and a key intermediate in the synthesis of modified nucleic acids. This compound is critical for research and development in advanced pharmaceutical chemistry, particularly for creating novel antiviral and anticancer agents. It is primarily utilized by fine chemical manufacturers, pharmaceutical R&D laboratories, and biotechnology companies engaged in oligonucleotide and prodrug synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of nucleoside-based antiviral and anticancer drugs.
• Oligonucleotide Synthesis: Used in the research and production of modified oligonucleotides for therapeutic and diagnostic applications.
• Prodrug Development: Serves as a precursor in the design of prodrugs to enhance drug delivery and bioavailability.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies related to nucleic acid metabolism.
• Fine Chemical Synthesis: A versatile intermediate for creating complex molecules in medicinal chemistry and chemical biology.
• Academic & Industrial R&D: Supports discovery programs in universities and corporate research centers focused on genetic medicine.

Basic Information

Product Name	5-(2,4-Dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolane-2-carboxylic Acid
CAS No.	3415-07-4
Molecular Formula	C9H10N2O7
Molecular Weight	258.19 g/mol
Synonyms	1-(2-Carboxy-3,4-dihydroxy-tetrahydrofuran-2-yl)uracil; 1-(2-Carboxy-3,4-dihydroxy-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxylic acid; Uracil-1-yl-tetrahydrofuran carboxylic acid derivative; 1-(2-Carboxy-3,4-dihydroxy-2-tetrahydrofuranyl)uracil; 5-(Uracil-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(2,4-Dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolane-2-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.