Description

9-(2-Deoxy-α-D-Erythro-Pentofuranosyl)-9H-Purin-6-Amine is a high-purity nucleoside derivative, a critical building block in pharmaceutical and biochemical research. Its primary value lies in its role as a key intermediate for the synthesis of nucleoside analogs and oligonucleotides, which are fundamental to antiviral and anticancer drug development. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent industries who require reliable, high-quality raw materials for advanced therapeutic and diagnostic applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or standard in enzymatic studies and metabolic pathway analysis.
• Oligonucleotide Synthesis: Serves as a protected nucleoside building block for solid-phase synthesis of DNA and RNA fragments.
• Diagnostic Reagent Development: Employed in the formulation of probes and assay components for molecular diagnostics.
• Academic & Contract Research: A key material for universities and CROs conducting research in medicinal chemistry and molecular biology.
• Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method validation in GMP environments.

Basic Information

Product Name	9-(2-Deoxy-α-D-Erythro-Pentofuranosyl)-9H-Purin-6-Amine
CAS No.	3413-66-9
Molecular Formula	C10H13N5O3
Molecular Weight	251.24 g/mol
Synonyms	2'-Deoxyadenosine; Deoxyadenosine; 2'-Deoxy-D-adenosine; Adenine deoxyriboside; dA; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)adenine; 2'-Deoxy-D-adenosine; dAdo
EINECS	222-311-8

Quality Control

Our 9-(2-Deoxy-α-D-Erythro-Pentofuranosyl)-9H-Purin-6-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤10 ppm
Specific Rotation	-25° to -30° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.