Description

Methylthioadenosine Sulfoxide is a key biochemical intermediate and a derivative of the essential nucleoside S-adenosylmethionine (SAM). This compound is of significant interest in biochemical research and pharmaceutical development due to its role in polyamine and methionine salvage pathways. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and biotechnology sectors for enzyme studies, metabolic pathway analysis, and as a reference standard.

Application

• Biochemical Research: Used as a critical substrate or inhibitor in enzymatic studies, particularly for methylthioadenosine phosphorylase (MTAP) and other enzymes involved in sulfur metabolism.
• Pharmaceutical Development: Serves as a reference standard or starting material in the synthesis of novel therapeutic agents targeting metabolic disorders and cancers.
• Metabolic Pathway Analysis: Employed in cell culture and in vitro studies to investigate the methionine salvage and polyamine biosynthesis pathways.
• Diagnostic Reagent Manufacturing: Used in the formulation of diagnostic kits and assays for measuring enzyme activity or metabolite levels in clinical samples.
• Academic Research: A vital tool for universities and research institutions studying nucleotide metabolism, cell signaling, and apoptosis.

Basic Information

Product Name	Methylthioadenosine Sulfoxide
CAS No.	3387-65-3
Molecular Formula	C11H15N5O4S
Molecular Weight	313.34 g/mol
Synonyms	5'-Deoxy-5'-(methylsulfinyl)adenosine; 5'-S-Methyl-5'-thioadenosine Sulfoxide; 5'-Methylthioadenosine Sulfoxide; MTA Sulfoxide; 5'-Deoxy-5'-(methylsulfinyl)-5'-adenosine; 5'-(Methylsulfinyl)-5'-deoxyadenosine; S-Methyl-5'-thioadenosine Sulfoxide
EINECS	Contact for details

Quality Control

Our Methylthioadenosine Sulfoxide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.