Description

(2-Phenylethyl)Phosphonic Acid Ethyl 4-Nitrophenyl Ester is a specialized organophosphorus compound that serves as a critical synthetic intermediate and functional building block. Its unique structure, featuring both phosphonic acid ester and nitrophenyl groups, makes it valuable for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as catalyst development and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition where the phosphonate moiety acts as a bioisostere for phosphate groups.
• Agrochemical Research: Serves as a key precursor in the development of new herbicides, pesticides, and plant growth regulators that leverage its organophosphorus chemistry.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized phosphonate-based ligands for metal catalysis and asymmetric synthesis.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of advanced polymeric materials with specific thermal or chemical resistance properties.
• Chemical Biology Probe: Utilized in the design of activity-based probes for studying phosphatase and kinase enzyme functions in biological systems.

Basic Information

Product Name	(2-Phenylethyl)Phosphonic Acid Ethyl 4-Nitrophenyl Ester
CAS No.	3384-91-6
Molecular Formula	C₁₆H₁₈NO₅P
Molecular Weight	335.29 g/mol
Synonyms	Ethyl 4-Nitrophenyl (2-Phenylethyl)phosphonate; (2-Phenylethyl)phosphonic Acid Ethyl Ester 4-Nitrophenyl Ester; 4-Nitrophenyl Ethyl (2-Phenylethyl)phosphonate; Ethyl (2-Phenylethyl)phosphonate 4-Nitrophenyl Ester; Phosphonic Acid, (2-Phenylethyl)-, Ethyl Ester, 4-Nitrophenyl Ester; NSC 163063
EINECS	Contact for details

Quality Control

Our (2-Phenylethyl)Phosphonic Acid Ethyl 4-Nitrophenyl Ester is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.