Description

Methanesulfonic Acid 3β-Cholesteryl Ester is a specialized cholesteryl derivative where methanesulfonic acid is esterified at the 3-beta position of the cholesterol backbone. This compound serves as a crucial synthetic intermediate and a versatile building block in advanced organic and medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical development companies for the synthesis of novel steroidal compounds, prodrugs, and as a reference standard in analytical studies.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of novel steroidal drugs and prodrug candidates.
• Biochemical Research: Used in studies involving cholesterol metabolism, membrane biology, and lipid signaling pathways.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in HPLC, LC-MS, or NMR analysis.
• Prodrug Synthesis: Utilized to create bioreversible derivatives to enhance the solubility or bioavailability of therapeutic agents.
• Material Science: Potential precursor for creating functionalized steroidal liquid crystals or advanced organic materials.

Basic Information

Product Name	Methanesulfonic Acid 3β-Cholesteryl Ester
CAS No.	3381-54-2
Molecular Formula	C28H48O3S
Molecular Weight	464.75 g/mol
Synonyms	Cholesteryl Methanesulfonate; 3β-Cholest-5-en-3-yl Methanesulfonate; Cholest-5-en-3β-yl Methanesulfonate; 3β-Hydroxycholest-5-ene Methanesulfonate Ester; Methanesulfonic Acid Cholest-5-en-3β-yl Ester; Cholesterol 3β-Methanesulfonate; 3381-54-2
EINECS	Contact for details

Quality Control

Our Methanesulfonic Acid 3β-Cholesteryl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and loss on drying. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.