Description

2-Tolyl Chlorothioformate is a versatile organosulfur reagent primarily used as a key building block in organic synthesis. Its value lies in its role as a thioacylating agent, enabling the efficient introduction of the 2-tolylthiocarbonyl group into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thioamide or thiocarbamate functionalities.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the thiocarbonyl moiety is integral to biological activity.
• Polymer Chemistry: Acts as a modifying agent or chain-transfer agent in the synthesis of specialty polymers and resins.
• Chemical Research: Employed in academic and industrial R&D for constructing complex heterocycles and as a reagent in peptide mimetics development.
• Ligand and Catalyst Preparation: Utilized for the synthesis of sulfur-containing ligands used in metal catalysis and coordination chemistry.

Basic Information

Product Name	2-Tolyl Chlorothioformate
CAS No.	3370-38-5
Molecular Formula	C8H7ClOS
Molecular Weight	186.65 g/mol
Synonyms	o-Tolyl Chlorothioformate; 2-Methylphenyl Chlorothioformate; Chlorothioformic Acid O-Tolyl Ester; 2-Tolyl Chlorothiolformate; o-Tolyl Chlorothiolformate; (2-Methylphenyl) Carbonochloridothioate; Thiocarbonochloridic Acid O-Tolyl Ester
EINECS	222-155-6

Quality Control

Our 2-Tolyl Chlorothioformate is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.