Description

17β-Hydroxy-4α-Methyl-5α-Androstan-3-One Ethylene Acetal is a high-purity steroid intermediate characterized by its ethylene acetal-protected ketone group. This compound is a critical building block in the synthesis of more complex steroidal pharmaceuticals, offering enhanced stability and controlled reactivity for downstream chemical transformations. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within the fields of endocrinology and metabolic disease.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of advanced steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of new chemical entities.
• Hormone Analog Synthesis: Serves as a foundational scaffold for developing analogs with targeted biological activity.
• Process Chemistry: Employed in route scouting and optimization for scalable GMP manufacturing of steroid-based drugs.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in regulatory filings.

Basic Information

Product Name	17β-Hydroxy-4α-Methyl-5α-Androstan-3-One Ethylene Acetal
CAS No.	3347-76-0
Molecular Formula	C₂₂H₃₆O₃
Molecular Weight	348.52 g/mol
Synonyms	4α-Methyl-5α-androstane-3,17-dione ethylene acetal; 3,3-Ethylenedioxy-4α-methyl-5α-androstan-17β-ol; 17β-Hydroxy-4α-methyl-5α-androstan-3-one ethylene ketal; 4-Methyl-5α-androstane-3,17-dione cyclic ethylene acetal; 3,17-Dioxo-4α-methyl-5α-androstane ethylene acetal; 4-Methyl-androstanedione ethylene acetal; Androstane derivative 3347-76-0
EINECS	Contact for details

Quality Control

Our 17β-Hydroxy-4α-Methyl-5α-Androstan-3-One Ethylene Acetal is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.