Description

2'-O,3'-O-Benzylideneuridine is a protected nucleoside derivative, a key intermediate in the synthesis of modified oligonucleotides and other bioactive compounds. Its primary value lies in its role as a versatile building block for advanced pharmaceutical research, particularly in the development of antiviral and anticancer agents. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality raw materials for nucleoside chemistry and oligonucleotide synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside analogs with potential antiviral and anticancer activities.
• Oligonucleotide Synthesis: Serves as a protected monomer for the solid-phase or solution-phase synthesis of modified RNA and DNA strands for research and therapeutic applications.
• Biochemical Research: Used in studies exploring RNA structure, function, and stability, as well as in the development of molecular probes.
• Fine Chemical Synthesis: Employed as a specialized building block for creating complex molecules in medicinal chemistry and chemical biology.
• Academic & Industrial R&D: Essential for laboratories focused on nucleic acid chemistry, drug discovery, and the development of new therapeutic modalities.

Basic Information

Product Name	2'-O,3'-O-Benzylideneuridine
CAS No.	3257-71-4
Molecular Formula	C16H16N2O6
Molecular Weight	332.31 g/mol
Synonyms	Uridine, 2,3-O-(phenylmethylene)-; 2,3-O-Benzylideneuridine; 1-[(2R,3R,4R,5R)-3,4-(Phenylmethylidenedioxy)-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 2,3-O-Benzylidene-D-uridine; Benzylideneuridine; 2',3'-O-Benzylideneuridine; 2,3-O-(Phenylmethylene)uridine
EINECS	221-873-5

Quality Control

Our 2'-O,3'-O-Benzylideneuridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.