Description

Benzoyl Chloride, 2-Hydroxy-5-Nitro- is a specialized aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functional groups, which allow for selective reactions to create complex molecules with high precision. This compound is essential for research chemists and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop new active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a nitro-substituted benzoyl moiety.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators where its specific substitution pattern imparts desired biological activity.
• Dye and Pigment Production: Acts as an intermediate for creating azo dyes and other complex colorants, contributing to color fastness and specific hue properties.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polymers, such as polyamides or polyesters with enhanced properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for Friedel-Crafts acylation and other reactions to introduce the 2-hydroxy-5-nitrobenzoyl group.
• Chemical Research: Utilized as a standard or reagent in methodological development and chemical biology studies.

Basic Information

Product Name	Benzoyl Chloride, 2-Hydroxy-5-Nitro-
CAS No.	3223-20-9
Molecular Formula	C7H4ClNO4
Molecular Weight	201.56 g/mol
Synonyms	5-Nitro-2-hydroxybenzoyl chloride; 2-Hydroxy-5-nitrobenzoyl chloride; 5-Nitrosalicyloyl chloride; 2-Hydroxy-5-nitro-benzoic acid chloride; 5-Nitro-2-hydroxybenzoic acid chloride; 5-Nitrosalicylic acid chloride; o-Hydroxy-p-nitrobenzoyl chloride; (2-Hydroxy-5-nitrophenyl)(chloro)methanone
EINECS	221-749-5

Quality Control

Our Benzoyl Chloride, 2-Hydroxy-5-Nitro- is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and industry standards. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.