Description

11-Dehydrotetrahydrocorticosterone is a key intermediate and reference standard in the synthesis and analysis of corticosteroids and related steroid hormones. This compound is of significant value for research and development within the pharmaceutical and life sciences sectors, providing a critical building block for metabolic studies and drug discovery. It is primarily utilized by manufacturers and research institutions focused on endocrinology, analytical chemistry, and the development of steroidal therapeutics.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthetic pathways for various corticosteroid drugs and hormone analogs.
• Biochemical Research: Used as a reference standard in metabolic pathway studies, particularly those involving glucocorticoid metabolism and the HPA (hypothalamic-pituitary-adrenal) axis.
• Analytical Standard: Serves as a high-purity calibration standard for analytical techniques such as HPLC, LC-MS, and GC-MS in quality control and research laboratories.
• Endocrinology Studies: Employed in in-vitro and in-vivo research to investigate steroid hormone function, receptor binding, and enzymatic conversion.
• Diagnostic Development: Used in the development and validation of diagnostic assays and kits for measuring steroid hormone levels.

Basic Information

Product Name	11-Dehydrotetrahydrocorticosterone
CAS No.	3198-41-2
Molecular Formula	C21H32O4
Molecular Weight	348.48 g/mol
Synonyms	11-Dehydrotetrahydrocorticosterone; 5β-Pregnane-3α,21-diol-11,20-dione; 3α,21-Dihydroxy-5β-pregnane-11,20-dione; 11-Dehydro-THB; Tetrahydro-11-dehydrocorticosterone; 11-Dehydrotetrahydro compound B; 11-DH-THB; 5β-Pregnan-3α,21-diol-11,20-dione
EINECS	Contact for details

Quality Control

Our 11-Dehydrotetrahydrocorticosterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.