Description

2',3',5'-Tri-o-Acetylinosine is a key acetylated derivative of the nucleoside inosine, widely utilized as a protected intermediate in organic synthesis. This compound is essential for researchers and manufacturers requiring precise control over nucleoside chemistry for the development of novel compounds. It is primarily sought after by the pharmaceutical, biotechnology, and fine chemical industries for applications in nucleoside analog synthesis and oligonucleotide research.

Application

• Pharmaceutical Intermediate: Serves as a crucial protected building block in the synthesis of nucleoside analogs and antiviral/anticancer drug candidates.
• Oligonucleotide Synthesis: Used in the preparation of modified oligonucleotides for research and therapeutic applications.
• Biochemical Research: Acts as a substrate or intermediate in enzymatic studies and metabolic pathway investigations.
• Fine Chemical Synthesis: Employed as a specialized reagent for introducing the inosine moiety into complex molecular architectures.
• Protecting Group Chemistry: The acetyl groups provide temporary protection for the ribose hydroxyls during multi-step synthetic sequences.

Basic Information

Product Name	2',3',5'-Tri-o-Acetylinosine
CAS No.	3181-38-2
Molecular Formula	C16H18N4O8
Molecular Weight	394.34 g/mol
Synonyms	2',3',5'-Tri-O-acetylinosine; Inosine 2',3',5'-triacetate; 9-[(2R,3R,4R,5R)-3,4-Diacetoxy-5-(acetoxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one; 1,9-Dihydro-9-[(2R,3R,4R,5R)-3,4-diacetoxy-5-(acetoxymethyl)tetrahydro-2-furanyl]-6H-purin-6-one; Triacetyl Inosine; Inosine Triacetate
EINECS	221-690-9

Quality Control

Our 2',3',5'-Tri-o-Acetylinosine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.