Description

1-(β-D-Glucopyranosyl)-5-Methylpyrimidine-2,4(1H,3H)-Dione is a nucleoside analog where a glucopyranosyl moiety is linked to a methylated uracil base. This compound is significant as a key intermediate in the synthesis of modified nucleosides and potential pharmaceutical agents, offering a versatile scaffold for biochemical research and drug development. It is primarily required by research institutions and pharmaceutical companies engaged in antiviral, anticancer, and metabolic disorder research, as well as by fine chemical manufacturers producing specialized biochemical reagents.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving glycosyltransferases and nucleoside-metabolizing enzymes.
• Probe Development: Acts as a starting material for creating fluorescent or radiolabeled probes to study nucleic acid metabolism and cellular uptake mechanisms.
• Glycoconjugate Synthesis: Employed in the preparation of complex glycoconjugates and carbohydrate-modified biomolecules for structural and functional studies.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	1-(β-D-Glucopyranosyl)-5-Methylpyrimidine-2,4(1H,3H)-Dione
CAS No.	3180-78-7
Molecular Formula	C11H16N2O7
Molecular Weight	288.25 g/mol
Synonyms	5-Methyl-2'-deoxyuridine β-D-glucopyranoside; 5-Methyldeoxyuridine glucoside; Thymidine β-D-glucopyranoside; 1-(β-D-Glucopyranosyl)thymine; 5-Methyluridine β-D-glucoside; Glucosylthymine; 3180-78-7; NSC 401005
EINECS	221-682-6

Quality Control

Our 1-(β-D-Glucopyranosyl)-5-Methylpyrimidine-2,4(1H,3H)-Dione is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.