Description

5-Formyluridine is a modified nucleoside derivative of uridine, featuring a formyl group at the 5-position of the pyrimidine ring. This specific modification makes it a valuable building block and intermediate in the synthesis of more complex nucleoside analogs and oligonucleotides. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in drug discovery, nucleic acid chemistry, and biochemical research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based therapeutics, including potential antiviral and anticancer agents.
• Oligonucleotide Synthesis: Used as a modified monomer to introduce specific functionalities into synthetic DNA or RNA strands for research and diagnostic applications.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate nucleic acid metabolism and repair pathways.
• Proteomics & Molecular Biology: Can be incorporated into probes or tags for studying nucleic acid-protein interactions.
• Reference Standard: Employed as a high-purity analytical standard in quality control and method development for HPLC or LC-MS.
• Academic Research: Fundamental research tool in organic chemistry and medicinal chemistry for exploring structure-activity relationships (SAR).

Basic Information

Product Name	5-Formyluridine
CAS No.	3180-21-0
Molecular Formula	C10H12N2O7
Molecular Weight	272.21 g/mol
Synonyms	5-Carboxaldehydeuridine; 5-Formyl-2'-deoxyuridine (common misnomer, verify structure); 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-formylpyrimidine-2,4(1H,3H)-dione; Uridine, 5-formyl-; 5-FOrdU (abbreviation); 5-FO-dU (abbreviation); 5-Formyl-Urd
EINECS	221-673-5

Quality Control

Our 5-Formyluridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.