Description

3-Hydroxyphenylisothiocyanate is a versatile aromatic isothiocyanate derivative, a key building block in organic synthesis. Its reactive isothiocyanate group and phenolic hydroxyl functionality make it a valuable precursor for creating heterocyclic compounds and advanced materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in the synthesis of benzothiazole and benzimidazole derivatives with potential biological activity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structure serves as a core for bioactive molecules.
• Ligand and Chelating Agent Precursor: The phenolic -OH and isothiocyanate (-NCS) groups allow for the creation of complexing agents and ligands for metal catalysis and extraction processes.
• Polymer Modification: Acts as a reactive monomer or cross-linking agent for synthesizing specialty polymers with tailored thermal or mechanical properties.
• Bioconjugation and Probe Synthesis: Useful in biochemical research for labeling proteins or other biomolecules due to the reactivity of the isothiocyanate group with amines.
• Dye and Pigment Intermediate: Serves as a building block in the synthesis of complex organic dyes and colorants.

Basic Information

Product Name	3-Hydroxyphenylisothiocyanate
CAS No.	3125-63-1
Molecular Formula	C7H5NOS
Molecular Weight	151.19 g/mol
Synonyms	3-Hydroxyphenyl isothiocyanate; m-Hydroxyphenyl isothiocyanate; 3-Isothiocyanatophenol; Isocyanic acid, 3-hydroxyphenyl ester; Phenol, 3-isothiocyanato-; 1-Hydroxy-3-isothiocyanatobenzene
EINECS	221-502-8

Quality Control

Our 3-Hydroxyphenylisothiocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.