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Sodium ((2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl)Methyl Hydrogenphosphate CAS NO 3106-18-1


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CAS No.:3106-18-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Sodium ((2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl)Methyl Hydrogenphosphate is the sodium salt of 5'-UMP (uridine 5'-monophosphate), a fundamental nucleotide building block. This high-purity biochemical is critical for research and development in life sciences, ensuring reliable and reproducible results. It is primarily utilized by pharmaceutical companies, diagnostic manufacturers, and academic research institutions for applications in molecular biology, enzymology, and as a precursor in oligonucleotide synthesis.

Application

  • Biochemical Research & Development: Essential substrate and reference standard in enzymatic studies, metabolic pathway analysis, and nucleotide-related research.
  • Pharmaceutical Intermediates: Serves as a key starting material or intermediate in the synthesis of nucleoside-based antiviral drugs and other therapeutic agents.
  • Diagnostic Reagent Manufacturing: Used in the formulation of diagnostic kits, particularly those involving enzymatic assays and molecular detection systems.
  • Cell Culture & Media Supplements: Acts as a component in specialized cell culture media to support specific metabolic functions in vitro.
  • Oligonucleotide Synthesis: Employed as a protected or unprotected monomer in the chemical and enzymatic synthesis of RNA and DNA sequences.
  • Enzyme Cofactor Studies: Utilized in research focused on kinases, phosphorylases, and other enzymes that interact with uridine nucleotides.

Basic Information

Product Name Sodium ((2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl)Methyl Hydrogenphosphate
CAS No. 3106-18-1
Molecular Formula C9H11N2NaO9P
Molecular Weight 348.15 g/mol
Synonyms 5'-UMP Sodium Salt; Uridine 5'-Monophosphate Disodium Salt; Disodium Uridylate; UMP-Na2; Sodium Uridylate; Uridine-5'-monophosphoric Acid Disodium Salt; 5'-Uridylic Acid Disodium Salt; UMP Disodium Salt
EINECS 221-452-0

Quality Control

Our Sodium Uridine 5'-Monophosphate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥ 98.0%
pH (5% Solution) 7.0 - 9.0
Water Content (KF) ≤ 5.0%
Heavy Metals (as Pb) ≤ 10 ppm
Residual Solvents (GC) Meets ICH guidelines
Bacterial Endotoxins < 0.25 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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