Description

Halcinonide is a potent synthetic corticosteroid belonging to the glucocorticoid class, widely recognized for its significant anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for formulating effective topical dermatological treatments. It is primarily utilized by pharmaceutical manufacturers and compounding pharmacies to produce creams, ointments, and lotions for managing severe skin conditions. Halcinonide CAS NO 3093-35-4 offers reliable performance in targeted therapeutic applications.

Application

• Topical Corticosteroid Formulations: Primary use in prescription-strength creams, ointments, gels, and lotions for treating severe inflammatory skin disorders.
• Dermatology Pharmaceuticals: Key API for medications targeting psoriasis, eczema, contact dermatitis, and other steroid-responsive dermatoses.
• Compounding Pharmacy: Used by specialized pharmacies to prepare customized topical preparations for patients with specific needs or sensitivities.
• Veterinary Dermatology: Incorporated into topical treatments for inflammatory skin conditions in animals under veterinary supervision.
• Clinical Research: Serves as a reference standard and active component in studies investigating new topical delivery systems or comparative efficacy.

Basic Information

Product Name	Halcinonide
CAS No.	3093-35-4
Molecular Formula	C₂₄H₃₂ClFO₆
Molecular Weight	454.96 g/mol
Synonyms	21-Chloro-9-fluoro-11β,16α,17-trihydroxypregna-1,4-diene-3,20-dione 16,17-acetonide; Halog; SQ-18566; 21-Chloro-9-fluoro-11β-hydroxy-16α,17-(1-methylethylidene)bis(oxy)pregna-1,4-diene-3,20-dione; 9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone 21-chloro; Halcimonide; Halcinonidum
EINECS	221-444-7

Quality Control

Our Halcinonide is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical actives. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles, with methods aligned with major pharmacopoeias. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.