Description

12β-Acetyloxy-5α-Pregnan-20-One is a high-purity steroid derivative and a key synthetic intermediate in pharmaceutical research and development. This compound is valued for its precise chemical structure, which serves as a crucial building block for the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of advanced steroid hormones and related therapeutic compounds.
• Research & Development: Used in academic and industrial laboratories for pharmacological studies and the development of new drug candidates targeting steroid receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis using techniques like HPLC and GC-MS.
• Biochemical Synthesis: Employed in the synthesis of labeled compounds (e.g., deuterated or radiolabeled analogs) for metabolic and tracer studies.

Basic Information

Product Name	12β-Acetyloxy-5α-Pregnan-20-One
CAS No.	3002-93-5
Molecular Formula	C23H36O3
Molecular Weight	360.53 g/mol
Synonyms	12β-Acetoxypregnan-20-one; 20-Oxo-5α-pregnan-12β-yl acetate; 5α-Pregnan-12β-ol-20-one acetate; 12β-Hydroxy-5α-pregnan-20-one acetate; 12β-Acetoxy-5α-pregnan-20-one; Pregnan-12β-ol-20-one, acetate, (5α)-; (5α,12β)-12-(Acetyloxy)pregnan-20-one
EINECS	Contact for details

Quality Control

Our 12β-Acetyloxy-5α-Pregnan-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and control of specific impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.