Description

8-[(3S,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1,3-Dimethyl -7H-Purine-2,6-Dione is a high-purity nucleoside derivative, also known as 1,3-Dimethylxanthosine, which serves as a critical building block and reference standard in advanced biochemical research and pharmaceutical development. Its precise stereochemistry and defined structure make it an essential intermediate for synthesizing modified nucleosides and exploring novel therapeutic agents. This compound is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on antiviral drug discovery, metabolic pathway studies, and the development of diagnostic tools.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, particularly those involving methyltransferases and purine metabolism pathways.
• Diagnostic Reagent Development: Serves as a core component in developing assay kits for detecting specific enzymatic activities or metabolic disorders.
• Life Science Research: Employed in cell culture studies and molecular biology research to investigate cellular signaling and nucleotide-related processes.
• Academic Research: Utilized in universities and research institutes for fundamental studies in organic chemistry, medicinal chemistry, and chemical biology.
• Standards and Metrology: Acts as a certified reference material (CRM) for quality control and analytical method validation in pharmaceutical analysis.

Basic Information

Product Name	8-[(3S,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1,3-Dimethyl -7H-Purine-2,6-Dione
CAS No.	3001-44-3
Molecular Formula	C12H16N4O6
Molecular Weight	312.28 g/mol
Synonyms	1,3-Dimethylxanthosine; 1,3-Dimethylxanthine riboside; 1,3-Dimethyl-9-β-D-ribofuranosylxanthine; 1,3-Dimethyl-9-ribosylxanthine; 8-(β-D-Ribofuranosyl)-1,3-dimethylxanthine; 1,3-Dimethyl-9-(β-D-ribofuranosyl)xanthine; 1,3-Dimethyl-9-β-D-ribofuranosyl-3,9-dihydro-1H-purine-2,6-dione; 1,3-Dimethyl-9-(β-D-ribofuranosyl)uric acid
EINECS	221-104-8

Quality Control

Our 8-[(3S,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1,3-Dimethyl -7H-Purine-2,6-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all test results are available upon request. We support compliance with relevant guidelines for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.