Description

(2,4-Difluoro-Phenoxy)-Acetyl Chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. This compound matters for its role as a key building block in the creation of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research institutions and industrial manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those with fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides and pesticides, leveraging the phenoxy-acetyl chloride moiety.
• Liquid Crystal & OLED Material Production: Serves as a building block for fluorinated organic electronic materials.
• Polymer Modification: Employed to introduce specific functional groups into polymer chains for enhanced material properties.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke client projects.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new fluorinated compound libraries.

Basic Information

Product Name	(2,4-Difluoro-Phenoxy)-Acetyl Chloride
CAS No.	399-42-8
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	2,4-Difluorophenoxyacetyl Chloride; Acetyl chloride, (2,4-difluorophenoxy)-; (2,4-Difluorophenoxy)acetyl Chloride; 2-(2,4-Difluorophenoxy)acetyl Chloride; α-Chloro-2,4-difluorophenoxyacetone; (2,4-Difluorophenoxy)ethanoyl Chloride; NSC 403107; 399-42-8
EINECS	Contact for details

Quality Control

Our (2,4-Difluoro-Phenoxy)-Acetyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.