Description

2,5-Bis(Trifluoromethyl)Benzoyl Chloride is a high-value, multi-functional aromatic acid chloride derivative. This compound is a critical building block in advanced organic synthesis, prized for its ability to introduce the highly electron-withdrawing and lipophilic bis(trifluoromethyl)benzoyl moiety. It is essential for manufacturers and R&D chemists in the pharmaceutical, agrochemical, and specialty materials sectors who require precise and reliable intermediates for creating complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl groups contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Employed to introduce fluorinated aromatic units into polymer chains, enhancing chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation and nucleophilic acyl substitution reactions to form amides, esters, and ketones.
• Advanced Material Research: Utilized in R&D for developing new fluorinated compounds with unique electronic or optical characteristics.

Basic Information

Product Name	2,5-Bis(Trifluoromethyl)Benzoyl Chloride
CAS No.	393-82-8
Molecular Formula	C10H3ClF6O
Molecular Weight	288.57 g/mol
Synonyms	2,5-Bis(trifluoromethyl)benzoyl chloride; α,α,α,α',α',α'-Hexafluoro-2,5-xylyloyl chloride; 2,5-Bis(trifluoromethyl)benzoic acid chloride; Benzoyl chloride, 2,5-bis(trifluoromethyl)-; 2,5-Di(trifluoromethyl)benzoyl chloride; 2,5-Bis(trifluoromethyl)benzoylchloride; 2,5-Bis(trifluoromethyl)benzoylchlorid (German); 2,5-双(三氟甲基)苯甲酰氯 (Chinese)
EINECS	Contact for details

Quality Control

Our 2,5-Bis(Trifluoromethyl)Benzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, alcohols, and amines. Recommended storage temperature is 2-8°C for long-term stability. The material is moisture-sensitive; keep container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.