Description

17Alpha-Hydroxypregnenolone is a key steroid intermediate and a biosynthetic precursor in the production of various hormones. This compound matters for its critical role in the synthesis of corticosteroids, androgens, and other specialized steroid derivatives. It is primarily needed by pharmaceutical manufacturers, research institutions, and fine chemical producers engaged in steroid chemistry and hormone-related product development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of corticosteroids like hydrocortisone and more complex steroid-based APIs.
• Research & Development: Used in biochemical research to study steroidogenesis, enzyme pathways, and hormone metabolism.
• Fine Chemical Synthesis: Serves as a starting material for the production of specialized androgens and other steroid derivatives.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biochemical Studies: Utilized in in-vitro studies to investigate the function and regulation of 17α-hydroxylase and other enzymes.

Basic Information

Product Name	17Alpha-Hydroxypregnenolone
CAS No.	387-79-1
Molecular Formula	C21H32O3
Molecular Weight	332.48 g/mol
Synonyms	17α-Hydroxypregnenolone; 3β,17α-Dihydroxypregn-5-en-20-one; 17α-Hydroxy-5-pregnen-3β-ol-20-one; 17α-Hydroxydihydroprogesterone; Pregnenolone, 17α-hydroxy-; 17α-OH-Pregnenolone
EINECS	206-867-1

Quality Control

Our 17Alpha-Hydroxypregnenolone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets exacting standards for pharmaceutical intermediates and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.