Description

Allyl Trifluoroacetate is a versatile fluorinated organic ester, a key building block in advanced chemical synthesis. Its primary value lies in its trifluoroacetyl group, which serves as a powerful protecting group and a precursor for introducing fluorine atoms into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly where the trifluoroacetate moiety is required for bioactivity or metabolic stability.
• Agrochemical Synthesis: Serves as a key precursor for manufacturing advanced herbicides, fungicides, and insecticides that benefit from fluorine's unique properties.
• Fluorine Chemistry Reagent: Acts as a trifluoroacetylating agent in organic synthesis to introduce the CF3CO- group into alcohols, amines, and other nucleophiles.
• Polymer & Material Science: Employed in the production of specialty polymers and coatings, where the allyl group allows for cross-linking and polymerization reactions.
• Protecting Group Chemistry: Utilized as a protecting group for alcohols and amines in multi-step synthetic routes, which can be removed under mild conditions.
• Ligand & Catalyst Development: Used in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	Allyl Trifluoroacetate
CAS No.	383-67-5
Molecular Formula	C5H5F3O2
Molecular Weight	154.09 g/mol
Synonyms	2-Propen-1-yl trifluoroacetate; Allyl ester of trifluoroacetic acid; Trifluoroacetic acid allyl ester; 3-Trifluoroacetoxypropene; Allyl perfluoroacetate; 1-Propene-3-yl trifluoroacetate; 3-Trifluoroacetoxy-1-propene
EINECS	206-848-2

Quality Control

Our Allyl Trifluoroacetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile and hygroscopic nature, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term stability and to minimize moisture uptake. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.335 - 1.345
Density (20°C)	1.25 - 1.30 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.