Description

3,3,3-Trifluoro-2-(Trifluoromethyl)Propionyl Fluoride is a highly fluorinated acyl fluoride building block of significant interest in advanced organic synthesis. Its value lies in its unique perfluorinated structure, which serves as a key precursor for introducing trifluoromethyl and perfluoroalkyl groups into target molecules, thereby modifying their physical and chemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, where precise fluorination is required to enhance metabolic stability, lipophilicity, or material performance. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs) with fluorinated motifs to improve bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where fluorination increases efficacy and environmental persistence.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier in the synthesis of specialty polymers, coatings, and elastomers with enhanced chemical, thermal, and solvent resistance.
• Liquid Crystal & Electronic Chemicals: Employed in the manufacture of fluorinated liquid crystals and dielectric fluids for the electronics industry.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the -COCF(CF3)2 group into complex organic molecules via acylation reactions.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new fluorination methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	3,3,3-Trifluoro-2-(Trifluoromethyl)Propionyl Fluoride
CAS No.	382-22-9
Molecular Formula	C4HF7O
Molecular Weight	210.04 g/mol
Synonyms	Perfluoroisobutyryl Fluoride; 2-(Trifluoromethyl)-3,3,3-trifluoropropanoyl Fluoride; Heptafluoroisobutyryl Fluoride; PFIBF; 1,1,1,3,3,3-Hexafluoro-2-(trifluoromethyl)propan-2-one Fluoride; Iso-C4F7OF; Perfluoro(2-methylpropionyl) Fluoride
EINECS	206-851-7

Quality Control

Our 3,3,3-Trifluoro-2-(Trifluoromethyl)Propionyl Fluoride is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and FTIR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, this material must be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from moisture, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.