Description

5H-Octafluoropentanoyl Bromide is a highly fluorinated acyl bromide intermediate, characterized by its reactive carbonyl bromide group and perfluorinated alkyl chain. This compound is critical for introducing the perfluoropentanoate moiety into target molecules, enabling the synthesis of materials with enhanced chemical stability, hydrophobicity, and unique surface properties. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex fluorinated compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and prodrugs to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced fluorinated pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Fluorinated Polymer & Material Science: Serves as a monomer or grafting agent for creating specialty fluoropolymers, coatings, and surfactants with oil- and water-repellent characteristics.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated liquid crystals and dielectric fluids for high-performance display and electronic applications.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation and nucleophilic acyl substitution reactions under controlled conditions to install fluorinated chains.
• Surface Modification Agent: Used to derivatize surfaces (e.g., silica, polymers) to impart permanent fluorinated properties for low-energy coatings.

Basic Information

Product Name	5H-Octafluoropentanoyl Bromide
CAS No.	376-69-2
Molecular Formula	C5HBrF8O
Molecular Weight	288.95 g/mol
Synonyms	Perfluoropentanoyl Bromide; Octafluoropentanoyl Bromide; Pentafluoropropionyl Bromide, Trifluoro-; 4,4,5,5,6,6,7,7,7-Nonafluoroheptanoyl Bromide (related isomer); 2,2,3,3,4,4,5,5-Octafluoropentanoyl Bromide; Perfluorovaleroyl Bromide; PFPeBr; 1-Bromo-2,2,3,3,4,4,5,5-octafluoropentan-1-one
EINECS	206-796-5

Quality Control

Our 5H-Octafluoropentanoyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Acidity (Titration)	≤ 0.5% (as HBr)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.