Description

Heptafluorobutanoyl Bromide CAS NO 375-13-3 is a highly reactive perfluorinated acyl bromide, serving as a critical fluorinated building block in advanced organic synthesis. Its primary value lies in introducing the heptafluorobutyryl group, which imparts unique properties like enhanced lipophilicity, metabolic stability, and chemical resistance to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, particularly for developing active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Key reagent for synthesizing fluorinated active pharmaceutical ingredients (APIs) and prodrugs to improve bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced, fluorinated pesticides and herbicides with enhanced efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, improving performance and stability.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing their chemical resistance, thermal stability, and surface properties.
• Analytical Chemistry: Utilized as a derivatization agent in gas chromatography and mass spectrometry for the analysis of amines, alcohols, and other compounds.
• Surface Treatment Agent: Serves as a precursor for creating low-surface-energy, oil- and water-repellent coatings.

Basic Information

Product Name	Heptafluorobutanoyl Bromide
CAS No.	375-13-3
Molecular Formula	C4BrF7O
Molecular Weight	280.94 g/mol
Synonyms	Perfluorobutyryl Bromide; Heptafluorobutyryl Bromide; 1-Bromo-1,1,2,2,3,3,3-heptafluoropropane; 2,2,3,3,4,4,4-Heptafluorobutanoyl Bromide; Perfluorobutanoic Acid Bromide; C3F7COBr; PFBBr; Heptafluorobutyric Acid Bromide
EINECS	206-791-5

Quality Control

Our Heptafluorobutanoyl Bromide is manufactured under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including GC, NMR, and titration, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to minimize volatility and degradation. Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Acidity (as HF)	≤ 0.05%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.