Description

Phenylacetyl Fluoride is a versatile and highly reactive organofluorine building block, essential for the efficient introduction of the phenylacetyl moiety. Its primary value lies in its superior reactivity as an acylating agent compared to other acid halides, enabling high-yield synthetic pathways. This compound is critically needed by research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel compounds and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of β-lactam antibiotics, peptides, and other active pharmaceutical ingredients (APIs) requiring phenylacetic acid derivatives.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the phenylacetyl group is a critical structural component.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers and resins to impart specific chemical or physical properties.
• Organic Synthesis Reagent: Employed as a high-reactivity acylating agent in Friedel-Crafts reactions, esterifications, and amide bond formations under mild conditions.
• Liquid Crystal & OLED Material Production: Serves as a precursor in the manufacturing of advanced electronic and display materials.
• Flavor & Fragrance Industry: Intermediate for the synthesis of certain aromatic compounds used in perfumery and flavoring agents.

Basic Information

Product Name	Phenylacetyl Fluoride
CAS No.	370-84-3
Molecular Formula	C8H7FO
Molecular Weight	138.14 g/mol
Synonyms	α-Toluoyl Fluoride; 2-Phenylacetyl Fluoride; Benzeneacetyl Fluoride; Phenylacetic Acid Fluoride; Phenylacetylfluoride; (Fluoroformyl)methylbenzene; Phenylacetylfluorid (German); Fluorure de phénylacétyle (French)
EINECS	206-732-2

Quality Control

Our Phenylacetyl Fluoride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including assay by GC/HPLC, identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent purity for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. Due to its hygroscopic (moisture-sensitive) and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and maintain product integrity. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.