Description

4-(Trifluoromethyl)Benzoyl Fluoride is a high-purity, reactive organofluorine building block essential for advanced chemical synthesis. Its core value lies in the trifluoromethyl and acyl fluoride functional groups, which enable efficient introduction of fluorinated aromatic moieties into target molecules. This compound is critically needed by R&D and production chemists in the pharmaceutical, agrochemical, and specialty materials industries for developing novel active ingredients and performance chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability via the trifluoromethyl group.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the CF3 group improves lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic components in electronic display and lighting materials.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: A versatile acylating agent and fluorinated aryl source in cross-coupling reactions and nucleophilic substitutions.
• Advanced Material Research: Used in R&D for creating novel fluorinated compounds with specific electronic or optical properties.

Basic Information

Product Name	4-(Trifluoromethyl)Benzoyl Fluoride
CAS No.	368-94-5
Molecular Formula	C8H4F4O
Molecular Weight	192.11 g/mol
Synonyms	p-(Trifluoromethyl)benzoyl fluoride; α,α,α-Trifluoro-p-toluoyl fluoride; 4-(Trifluoromethyl)benzoic acid fluoride; 4-(Trifluoromethyl)benzoyl fluoride; 4-Trifluoromethylbenzoyl fluoride; (4-Trifluoromethylphenyl)carbonyl fluoride; Benzoyl fluoride, 4-(trifluoromethyl)-
EINECS	206-719-3

Quality Control

Our 4-(Trifluoromethyl)Benzoyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizers, and sources of moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.