Description

1-[3,5-Bis(Trifluoromethyl)Phenyl]Ethan-1-Ol is a high-value fluorinated aromatic alcohol, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring electron-withdrawing trifluoromethyl groups, is essential for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potent drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity.
• Ligand & Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Incorporated into specialty polymers and liquid crystals to impart specific fluorinated properties.
• Chemical Research: Employed in academic and industrial R&D for method development and exploring new fluorination chemistry.

Basic Information

Product Name	1-[3,5-Bis(Trifluoromethyl)Phenyl]Ethan-1-Ol
CAS No.	368-63-8
Molecular Formula	C10H6F6O
Molecular Weight	256.15 g/mol
Synonyms	1-(3,5-Bis(trifluoromethyl)phenyl)ethanol; α-(3,5-Bis(trifluoromethyl)phenyl)ethanol; 1-[3,5-Bis(trifluoromethyl)phenyl]ethyl alcohol; (RS)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol; 3,5-Bis(trifluoromethyl)benzyl methyl alcohol (common misnomer); 2,2,2-Trifluoro-1-[3,5-bis(trifluoromethyl)phenyl]ethanol (incorrect but related); 3,5-Bis(trifluoromethyl)phenethyl alcohol (related); BTPE
EINECS	Contact for details

Quality Control

Our production of 1-[3,5-Bis(Trifluoromethyl)Phenyl]Ethan-1-Ol adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric excess (where applicable), and impurity profiles. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Enantiomeric Purity (Chiral HPLC)	Specify required ratio (R/S)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.