Description

1-[4-Fluoro-3-(Trifluoromethyl)Phenyl]Ethan-1-Ol is a high-value fluorinated aromatic alcohol, serving as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl groups, imparts desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Active Ingredient Precursor: Used in the development of advanced herbicides and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for fluorinated components in electronic display and lighting materials.
• Advanced Polymer Modification: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Asymmetric Catalysis & Ligand Development: Utilized as a substrate or precursor for chiral ligands and catalysts in enantioselective synthesis.
• Fluorine Chemistry Research: A valuable standard and reagent for studying structure-activity relationships (SAR) in medicinal and material chemistry.

Basic Information

Product Name	1-[4-Fluoro-3-(Trifluoromethyl)Phenyl]Ethan-1-Ol
CAS No.	367-69-1
Molecular Formula	C9H8F4O
Molecular Weight	208.15 g/mol
Synonyms	1-(4-Fluoro-3-(trifluoromethyl)phenyl)ethanol; α-Methyl-4-fluoro-α-(trifluoromethyl)benzenemethanol; 4-Fluoro-α-methyl-α-(trifluoromethyl)benzyl Alcohol; 1-(4-Fluoro-3-trifluoromethylphenyl)ethyl Alcohol; 2-(4-Fluoro-3-(trifluoromethyl)phenyl)propan-2-ol (tautomer); F3C-Ph-F-CH(OH)CH3; p-Fluoro-m-trifluoromethyl-α-methylbenzyl Alcohol
EINECS	Contact for details

Quality Control

Our production of 1-[4-Fluoro-3-(Trifluoromethyl)Phenyl]Ethan-1-Ol adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure consistency and meet the exacting requirements of advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support custom synthesis and can tailor specifications to meet specific GMP or research-grade standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed to minimize exposure to moisture and air. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Typical)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.