Description

5'-Thymidylic Acid Disodium Salt is a nucleotide derivative and the disodium salt of thymidine monophosphate. This compound serves as a critical building block and reference standard in molecular biology and pharmaceutical research. It is essential for researchers and manufacturers in the biotechnology, diagnostic, and life science sectors requiring high-purity nucleotide components.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for the solid-phase synthesis of DNA strands and probes.
• Biochemical Research: Used as a substrate, standard, or intermediate in enzymatic studies, metabolic pathway analysis, and nucleotide metabolism research.
• Diagnostic Reagent Manufacturing: Incorporated into the production of PCR kits, sequencing assays, and other molecular diagnostic tools.
• Pharmaceutical Development: Acts as an intermediate in the synthesis of antiviral and anticancer nucleoside analog prodrugs.
• Cell Culture Media: A component of specialized media formulations for cell growth and viability studies.
• Reference Standard: Used for calibration, identification, and quantification in analytical HPLC, LC-MS, and other quality control methods.

Basic Information

Product Name	5'-Thymidylic Acid Disodium Salt
CAS No.	365-07-1
Molecular Formula	C10H13N2Na2O8P
Molecular Weight	368.16 g/mol
Synonyms	Thymidine 5'-Monophosphate Disodium Salt; dTMP Disodium Salt; 5'-dTMP Na2; Thymidylic Acid Disodium Salt; Thymidine 5'-(Disodium Phosphate); 2'-Deoxythymidine 5'-Monophosphate Disodium Salt; TMP Disodium Salt; 5'-Thymidylic Acid Sodium Salt
EINECS	206-674-4

Quality Control

Our 5'-Thymidylic Acid Disodium Salt is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity suitable for research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material compliant with various internal specifications for pharmaceutical intermediates or molecular biology grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (5% solution)	7.0 - 9.0
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.