Description

1-[2,5-Bis(Trifluoromethyl)Phenyl]Ethan-1-Ol is a high-value fluorinated aromatic alcohol building block, prized for its unique electronic and steric properties imparted by the trifluoromethyl groups. This compound is essential for introducing lipophilicity and metabolic stability into advanced molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas requiring enhanced bioavailability and receptor binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for asymmetric catalysis and transition metal complexes.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to produce specialty polymers with specific thermal, chemical, or surface properties.
• Chemical Research & Development: A versatile building block in medicinal chemistry and material science R&D for exploring new chemical entities and functional groups.

Basic Information

Product Name	1-[2,5-Bis(Trifluoromethyl)Phenyl]Ethan-1-Ol
CAS No.	364-47-6
Molecular Formula	C10H6F6O
Molecular Weight	256.15 g/mol
Synonyms	2,5-Bis(trifluoromethyl)phenethyl alcohol; 1-(2,5-Bis(trifluoromethyl)phenyl)ethanol; α-Methyl-2,5-bis(trifluoromethyl)benzenemethanol; (2,5-Bis(trifluoromethyl)phenyl)methylcarbinol; 2,5-Bis(trifluoromethyl)benzeneethanol; 364-47-6; Ethan-1-ol, 1-[2,5-bis(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 1-[2,5-Bis(Trifluoromethyl)Phenyl]Ethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Melting Point	Contact for details
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.