Description

Fluorohydroxyandrostenedione is a fluorinated steroid derivative with significant biochemical activity. This compound is valued for its role as a potent and selective inhibitor of aromatase, an enzyme critical in estrogen biosynthesis. It is primarily utilized by pharmaceutical researchers and manufacturers in the development of therapeutic agents targeting hormone-dependent conditions, such as certain cancers and endocrine disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced steroid-based therapeutics.
• Aromatase Inhibition Research: Serves as a critical reference standard and active compound in studies focused on estrogen synthesis pathways.
• Oncology Drug Development: Used in R&D for creating treatments for hormone-sensitive cancers, including breast and prostate cancer.
• Endocrinology Studies: Employed in biochemical assays to investigate steroid metabolism and hormone regulation.
• Reference Standard: Provides a high-purity benchmark for analytical testing, quality control, and regulatory submissions in pharmaceutical manufacturing.

Basic Information

Product Name	Fluorohydroxyandrostenedione
CAS No.	357-09-5
Molecular Formula	C19H27FO3
Molecular Weight	322.42 g/mol
Synonyms	4-Hydroxy-4-androstene-3,17-dione, 6α-fluoro-; 6α-Fluoro-4-hydroxyandrost-4-ene-3,17-dione; Fluoxymesterone Impurity; 6-Fluoro-4-hydroxyandrost-4-ene-3,17-dione; 6α-Fluoro-4-hydroxyandrostenedione; Aromatase Inhibitor CGS 16949A; CGS-16949A
EINECS	Contact for details

Quality Control

Our Fluorohydroxyandrostenedione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.