Description

Thiocyanic Acid 4-Fluorobutyl Ester is a specialized organosulfur and organofluorine compound that serves as a valuable synthetic intermediate. Its unique bifunctional structure, featuring both a thiocyanate (-SCN) group and a fluorinated alkyl chain, makes it a versatile building block for introducing sulfur and fluorine atoms into target molecules. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates, particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, or functional materials with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes, leveraging the reactivity of the thiocyanate group.
• Organic Synthesis Reagent: Acts as an electrophilic fluorination source or a coupling partner in various cross-coupling reactions to construct complex molecular architectures.

Basic Information

Product Name	Thiocyanic Acid 4-Fluorobutyl Ester
CAS No.	353-17-3
Molecular Formula	C5H8FNOS
Molecular Weight	149.19 g/mol
Synonyms	4-Fluorobutyl Thiocyanate; 4-Fluorobutyl Isothiocyanate (common misnomer); 1-Fluoro-4-thiocyanatobutane; Butane, 1-fluoro-4-thiocyanato-; 4-Fluorobutyl rhodanide; NSC 406916; 4-Fluorobutyl ester of thiocyanic acid
EINECS	Contact for details

Quality Control

Our Thiocyanic Acid 4-Fluorobutyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and process development. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Research Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.