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3-(Trifluoromethyl)Benzyl Alcohol CAS NO 349-75-7


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CAS No.:349-75-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(Trifluoromethyl)Benzyl Alcohol is a versatile fluorinated aromatic alcohol, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the benzyl alcohol moiety and the electron-withdrawing trifluoromethyl group, which imparts desirable properties to final products. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine for enhanced bioactivity, metabolic stability, and lipophilicity.

Application

  • Pharmaceutical Intermediates: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-inflammatory agents.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
  • Liquid Crystal Materials: Serves as a fluorinated component in the manufacture of liquid crystal displays (LCDs) to modify dielectric anisotropy and viscosity.
  • Polymer & Resin Modifiers: Incorporated as a monomer or additive to enhance the chemical resistance, thermal stability, and surface properties of specialty polymers.
  • Organic Synthesis & Catalysis: A valuable reagent for introducing the (trifluoromethyl)benzyl group into complex molecules via etherification, esterification, or oxidation reactions.
  • Flavor & Fragrance Intermediates: Used in the controlled synthesis of fluorinated aromatic compounds for high-value fragrance ingredients.

Basic Information

Product Name 3-(Trifluoromethyl)Benzyl Alcohol
CAS No. 349-75-7
Molecular Formula C8H7F3O
Molecular Weight 176.14 g/mol
Synonyms α-(Trifluoromethyl)-m-tolyl Alcohol; (3-(Trifluoromethyl)phenyl)methanol; m-(Trifluoromethyl)benzyl Alcohol; 3-(Trifluoromethyl)benzenemethanol; Benzenemethanol, 3-(trifluoromethyl)-; 3-Trifluoromethylbenzyl Alcohol; 3-CF3-Benzyl Alcohol; m-Trifluoromethylbenzyl Alcohol
EINECS 206-493-3

Quality Control

Our 3-(Trifluoromethyl)Benzyl Alcohol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP standards where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (GC/HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Related Substances (GC/HPLC) ≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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