Description

1-[4-Chloro-3-(Trifluoromethyl)Phenyl]Ethan-1-Ol is a high-value fluorinated aromatic alcohol building block, essential for synthesizing advanced chemical intermediates. Its unique structure, featuring both chloro and trifluoromethyl substituents, provides significant advantages in modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and electro-optical materials.
• Chemical Research: A versatile building block in academic and industrial R&D for exploring new reactions and creating complex molecular architectures.
• Dye and Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments.

Basic Information

Product Name	1-[4-Chloro-3-(Trifluoromethyl)Phenyl]Ethan-1-Ol
CAS No.	348-84-5
Molecular Formula	C9H6ClF3O
Molecular Weight	222.59 g/mol
Synonyms	1-(4-Chloro-3-(trifluoromethyl)phenyl)ethanol; 2-(4-Chloro-3-(trifluoromethyl)phenyl)ethan-1-ol (common numbering); α-(4-Chloro-α,α,α-trifluoro-m-tolyl)ethanol; 4-Chloro-α,α,α-trifluoro-m-tolyl alcohol; 1-(4-Chloro-3-trifluoromethylphenyl)ethyl alcohol; 348-84-5; m-Chloro-α,α,α-trifluoromethylbenzyl alcohol (related); CF3-Ph-CH(OH)CH3 derivative
EINECS	Contact for details

Quality Control

Our production of 1-[4-Chloro-3-(Trifluoromethyl)Phenyl]Ethan-1-Ol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications and can tailor specifications to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.