Description

2-(Trifluoromethyl)Benzyl Alcohol is a versatile fluorinated aromatic alcohol characterized by a benzyl alcohol core substituted with a trifluoromethyl group at the ortho position. This unique structure imparts enhanced lipophilicity and metabolic stability, making it a critical building block for advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules, including active pharmaceutical ingredients (APIs) and novel crop protection agents. Its utility extends to materials science as a precursor for specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Employed in the production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Specialty Polymer Modifier: Incorporated to introduce fluorine into polymer chains, improving chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Used in various coupling reactions, esterifications, and etherifications to introduce the 2-(trifluoromethyl)benzyl moiety.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science research in academic and industrial laboratories.

Basic Information

Product Name	2-(Trifluoromethyl)Benzyl Alcohol
CAS No.	346-06-5
Molecular Formula	C8H7F3O
Molecular Weight	176.14 g/mol
Synonyms	α-(Trifluoromethyl)-o-toluenol; 2-(Trifluoromethyl)benzenemethanol; (2-(Trifluoromethyl)phenyl)methanol; o-(Trifluoromethyl)benzyl alcohol; 2-Trifluoromethylbenzyl alcohol; 1-Hydroxymethyl-2-trifluoromethylbenzene; Benzenemethanol, 2-(trifluoromethyl)-; 2-TFMBA
EINECS	206-470-1

Quality Control

Our 2-(Trifluoromethyl)Benzyl Alcohol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.