Description

2,2-Difluoro-1-Phenylethan-1-Ol is a valuable fluorinated alcohol building block characterized by a phenyl group and two fluorine atoms on the β-carbon. This unique structure makes it a versatile intermediate for introducing the difluoroethanol moiety into more complex molecules. It is primarily utilized in the synthesis of advanced pharmaceutical compounds and specialty agrochemicals where the fluorine atoms can enhance metabolic stability and bioavailability. Researchers and process chemists in fine chemical and life science industries rely on this compound for its role in creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated side chains.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where fluorination improves efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in electronic display technologies.
• Organic Synthesis & Catalysis: Employed in various organic transformations, including as a precursor for ligands or catalysts in asymmetric synthesis.
• Polymer Science: Can be incorporated as a monomer or modifier to create specialty polymers with unique surface properties or chemical resistance.
• Fluorine Chemistry Research: A valuable standard and reagent for academic and industrial research exploring new fluorination methodologies and compound libraries.

Basic Information

Product Name	2,2-Difluoro-1-Phenylethan-1-Ol
CAS No.	345-64-2
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	2,2-Difluoro-1-phenylethanol; α,α-Difluoro-β-hydroxyethylbenzene; 2,2-Difluoro-2-phenylethanol; (2,2-Difluoroethyl)benzene alcohol; Benzenemethanol, α,α-difluoro-; Phenyldifluoroethanol; DFPE; 345-64-2
EINECS	206-465-8

Quality Control

Our 2,2-Difluoro-1-Phenylethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay by GC/HPLC, water content (KF), and identification by FT-IR or NMR. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or compatible opaque material.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	≤ 1.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.