Description

1-Phenyl-2,2,3,3,3-Pentafluoro-1-Propanol is a specialized fluorinated alcohol derivative, valued for its unique combination of a hydrophobic pentafluoropropyl group and a reactive hydroxyl moiety. This compound is a critical building block and intermediate in advanced organic synthesis, particularly where the introduction of fluorine atoms is required to modulate the physical, chemical, and biological properties of target molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel compounds with enhanced stability, bioavailability, or specific electronic characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), especially for introducing fluorinated side chains that can improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorine incorporation often leads to increased efficacy and environmental persistence.
• Liquid Crystal & Electronic Materials: Acts as a precursor or dopant in the synthesis of fluorinated liquid crystals and organic semiconductors for display technologies and electronic devices.
• Polymer & Resin Modification: Employed to create fluorinated polymers, coatings, and resins with superior chemical resistance, low surface energy, and enhanced durability.
• Catalyst & Ligand Development: Utilized in the design of novel fluorinated ligands for metal-organic catalysis, enabling new reaction pathways and selectivities.
• Organic Synthesis Building Block: A versatile reagent for nucleophilic substitution, esterification, and other reactions to construct complex fluorinated organic molecules.

Basic Information

Product Name	1-Phenyl-2,2,3,3,3-Pentafluoro-1-Propanol
CAS No.	345-40-4
Molecular Formula	C9H7F5O
Molecular Weight	226.14 g/mol
Synonyms	α-Phenyl-2,2,3,3,3-pentafluoro-1-propanol; 2,2,3,3,3-Pentafluoro-1-phenyl-1-propanol; Pentafluoropropyl phenyl carbinol; (2,2,3,3,3-Pentafluoropropyl)phenylmethanol; 1-Phenylpentafluoropropanol; PFPP-OH; 345-40-4; Benzenemethanol, α-(2,2,3,3,3-pentafluoropropyl)-
EINECS	Contact for details

Quality Control

Our 1-Phenyl-2,2,3,3,3-Pentafluoro-1-Propanol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from laboratory to commercial scale, ensuring reliable supply for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.