Description

6-Methylmercaptopurine Riboside is a purine nucleoside analog of significant research and pharmaceutical interest. This compound serves as a key intermediate and reference standard in the development and study of chemotherapeutic agents and immunosuppressants. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in oncology, immunology, and metabolic pathway research.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of advanced purine-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and tool compound in studies of purine metabolism, enzyme inhibition, and nucleoside transport.
• Oncology Research: Investigated for its potential role in cancer therapy development due to its structural similarity to active antimetabolites.
• Immunosuppressant Studies: Employed in research exploring mechanisms for modulating immune response.
• Metabolic Pathway Analysis: A reagent for studying nucleotide salvage pathways and related enzymatic processes in vitro.
• Analytical Standard: High-purity grade material for use in HPLC, LC-MS, and NMR as a calibration standard for quality control laboratories.

Basic Information

Product Name	6-Methylmercaptopurine Riboside
CAS No.	342-69-8
Molecular Formula	C11H14N4O5S
Molecular Weight	314.32 g/mol
Synonyms	6-(Methylthio)-9-β-D-ribofuranosyl-9H-purine; 6-Methylmercaptopurine-9-riboside; 6-MMPR; NSC-40774; 6-Methylthiopurine ribonucleoside; 6-Methylthio-9-β-D-ribofuranosylpurine; 9-β-D-Ribofuranosyl-6-(methylthio)purine; 6-Methylmercaptopurine Ribonucleoside
EINECS	206-436-7

Quality Control

Our 6-Methylmercaptopurine Riboside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing the exact specifications and test results. Our quality commitment ensures material suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.