Description

(S)-(+)-α-(Trifluoromethyl)Benzyl Alcohol CAS NO 340-06-7 is a high-value, optically pure chiral building block characterized by its trifluoromethyl and benzyl alcohol functional groups. This compound matters for its critical role in asymmetric synthesis, where its defined stereochemistry is leveraged to induce chirality in complex pharmaceutical and agrochemical intermediates. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of active ingredients and specialty chemicals.

Application

• As a key chiral intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• In agrochemical research for constructing enantiomerically pure herbicides, fungicides, and plant growth regulators.
• As a versatile ligand or auxiliary in asymmetric catalysis and transition metal-mediated reactions.
• For the preparation of liquid crystals and advanced organic electronic materials requiring specific optical properties.
• In academic and industrial R&D for methodological studies in stereoselective synthesis and fluoroorganic chemistry.
• As a starting material for the synthesis of other high-value fluorinated fine chemicals and specialty monomers.

Basic Information

Product Name	(S)-(+)-α-(Trifluoromethyl)Benzyl Alcohol
CAS No.	340-06-7
Molecular Formula	C8H7F3O
Molecular Weight	176.14 g/mol
Synonyms	(S)-1-Phenyl-2,2,2-trifluoroethanol; (S)-α-(Trifluoromethyl)benzyl alcohol; (S)-(+)-1-Phenyl-2,2,2-trifluoroethanol; (S)-TFB Alcohol; (S)-Phenyltrifluoroethanol; (S)-Benzenemethanol, α-(trifluoromethyl)-; (S)-2,2,2-Trifluoro-1-phenylethanol; (S)-Trifluoromethylphenylcarbinol
EINECS	206-424-5

Quality Control

Our (S)-(+)-α-(Trifluoromethyl)Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Specific Rotation [α]D20	+15° to +18° (c=1 in ethanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.